Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAD9BRAD9 checkpoint clamp component B. (408 aa)    
Predicted Functional Partners:
ENSCAPP00000009577
annotation not available
    
 0.996
ATR
ATR serine/threonine kinase.
    
 0.982
RAD17
RAD17 checkpoint clamp loader component.
   
 0.976
TOPBP1
DNA topoisomerase II binding protein 1.
    
 0.973
ATM
ATM serine/threonine kinase.
    
 0.958
RFC2
Replication factor C subunit 2.
   
 0.957
RAD9A
RAD9 checkpoint clamp component A.
     
  0.947
RFC4
Replication factor C subunit 4.
   
 0.943
RPA1
Replication protein A1.
    
 0.940
WRN
WRN RecQ like helicase.
   
 0.940
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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