Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
TRAM2Translocation associated membrane protein 2. (343 aa)    
Predicted Functional Partners:
SEC63
SEC63 homolog, protein translocation regulator.
   
 
 0.687
DDOST
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit.
   
 
 0.646
DTL
Denticleless E3 ubiquitin protein ligase homolog.
      
 0.627
CTSB
Cathepsin B.
      
 0.626
PLN
Phospholamban.
      
 0.567
ATP2A3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3.
      
 0.567
MTMR9
Myotubularin related protein 9.
      
 0.553
MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase.
      
 0.519
ENSCAPP00000002863
annotation not available
    
 
 0.518
SPCS2
Signal peptidase complex subunit 2.
   
 
 0.515
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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