Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (280 aa)    
Predicted Functional Partners:
ORMDL3
ORMDL sphingolipid biosynthesis regulator 3.
    
 0.999
SPTLC3
Serine palmitoyltransferase long chain base subunit 3.
  
0.993
ENSCAPP00000011545
annotation not available
    
 0.992
ORMDL1
ORMDL sphingolipid biosynthesis regulator 1.
    
 0.991
ENSCAPP00000002799
annotation not available
   
 0.988
ISM1
Isthmin 1.
   
 0.979
KDSR
3-ketodihydrosphingosine reductase.
     
 0.968
SACM1L
SAC1 like phosphatidylinositide phosphatase.
   
 0.950
PCSK9
Proprotein convertase subtilisin/kexin type 9.
   
 0.949
GOLGA7B
Golgin A7 family member B.
   
 
  0.946
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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