Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MELTFMelanotransferrin. (755 aa)    
Predicted Functional Partners:
TFRC
Transferrin receptor.
  
 0.936
TFR2
Transferrin receptor 2.
  
 0.873
HFE
Homeostatic iron regulator.
    
 0.776
HJV
Hemojuvelin BMP co-receptor.
     
 0.723
ALDH16A1
Aldehyde dehydrogenase 16 family member A1.
    
 0.699
CLCA1
Chloride channel accessory 1.
    
 0.611
SRPRA
SRP receptor subunit alpha.
    
  0.582
BMPR1B
Bone morphogenetic protein receptor type 1B.
    
  0.574
BMPR1A
Bone morphogenetic protein receptor type 1A.
    
  0.574
APOB
Apolipoprotein B.
   
 0.570
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: high (82%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.