close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000005424annotation not available (236 aa)    
Predicted Functional Partners:
CDK4
Cyclin dependent kinase 4.
   
 0.997
CDK6
Cyclin dependent kinase 6.
   
 0.997
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.995
CDK2
Cyclin dependent kinase 2.
   
 0.982
RBL2
RB transcriptional corepressor like 2.
    
 0.979
RB1
RB transcriptional corepressor 1.
    
 0.966
RBL1
RB transcriptional corepressor like 1.
    
 0.963
PCNA
Proliferating cell nuclear antigen.
    
 0.959
CCND1
Cyclin D1.
  
  
0.912
ENSCAPP00000010633
annotation not available
     
0.911
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.