HOOK2 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

HOOK2

Hook microtubule tethering protein 2. (590 aa)

Predicted Functional Partners:

AKTIP

0.996

FAM160A2

0.987

HOOK3

0.971

VPS18

0.971

FAM160A1

0.968

VPS11

0.962

VPS41

0.953

VPS16

0.953

ENSCAPP00000018279

0.953

ENSCAPP00000000647

0.949

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKTIP	ENSCAPP00000000647	ENSCAPP00000018206	ENSCAPP00000000647	AKT interacting protein.	annotation not available	0.913
AKTIP	ENSCAPP00000018279	ENSCAPP00000018206	ENSCAPP00000018279	AKT interacting protein.	annotation not available	0.913
AKTIP	FAM160A1	ENSCAPP00000018206	ENSCAPP00000001105	AKT interacting protein.	Family with sequence similarity 160 member A1.	0.997
AKTIP	FAM160A2	ENSCAPP00000018206	ENSCAPP00000000382	AKT interacting protein.	Family with sequence similarity 160 member A2.	0.998
AKTIP	HOOK2	ENSCAPP00000018206	ENSCAPP00000005467	AKT interacting protein.	Hook microtubule tethering protein 2.	0.996
AKTIP	HOOK3	ENSCAPP00000018206	ENSCAPP00000016964	AKT interacting protein.	Hook microtubule tethering protein 3.	0.998
AKTIP	VPS11	ENSCAPP00000018206	ENSCAPP00000014625	AKT interacting protein.	VPS11 core subunit of CORVET and HOPS complexes.	0.940
AKTIP	VPS16	ENSCAPP00000018206	ENSCAPP00000016090	AKT interacting protein.	VPS16 core subunit of CORVET and HOPS complexes.	0.948
AKTIP	VPS18	ENSCAPP00000018206	ENSCAPP00000017791	AKT interacting protein.	VPS18 core subunit of CORVET and HOPS complexes.	0.951
AKTIP	VPS41	ENSCAPP00000018206	ENSCAPP00000005646	AKT interacting protein.	VPS41 subunit of HOPS complex.	0.950
ENSCAPP00000000647	AKTIP	ENSCAPP00000000647	ENSCAPP00000018206	annotation not available	AKT interacting protein.	0.913
ENSCAPP00000000647	ENSCAPP00000018279	ENSCAPP00000000647	ENSCAPP00000018279	annotation not available	annotation not available	0.963
ENSCAPP00000000647	HOOK2	ENSCAPP00000000647	ENSCAPP00000005467	annotation not available	Hook microtubule tethering protein 2.	0.949
ENSCAPP00000000647	HOOK3	ENSCAPP00000000647	ENSCAPP00000016964	annotation not available	Hook microtubule tethering protein 3.	0.963
ENSCAPP00000000647	VPS11	ENSCAPP00000000647	ENSCAPP00000014625	annotation not available	VPS11 core subunit of CORVET and HOPS complexes.	0.999
ENSCAPP00000000647	VPS16	ENSCAPP00000000647	ENSCAPP00000016090	annotation not available	VPS16 core subunit of CORVET and HOPS complexes.	0.999
ENSCAPP00000000647	VPS18	ENSCAPP00000000647	ENSCAPP00000017791	annotation not available	VPS18 core subunit of CORVET and HOPS complexes.	0.999
ENSCAPP00000000647	VPS41	ENSCAPP00000000647	ENSCAPP00000005646	annotation not available	VPS41 subunit of HOPS complex.	0.998
ENSCAPP00000018279	AKTIP	ENSCAPP00000018279	ENSCAPP00000018206	annotation not available	AKT interacting protein.	0.913
ENSCAPP00000018279	ENSCAPP00000000647	ENSCAPP00000018279	ENSCAPP00000000647	annotation not available	annotation not available	0.963