close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL18RAPInterleukin 18 receptor accessory protein. (591 aa)    
Predicted Functional Partners:
IL18R1
Interleukin 18 receptor 1.
   
0.997
IL18
Interleukin 18.
   
 0.989
IL1RAP
Interleukin 1 receptor accessory protein.
   
0.815
MYD88
MYD88 innate immune signal transduction adaptor.
   
 
 0.814
IL1R2
Interleukin 1 receptor type 2.
   
0.727
ENSCAPP00000012152
annotation not available
   
 0.649
IL36RN
Interleukin 36 receptor antagonist.
   
 0.646
ENSCAPP00000014109
annotation not available
  
  
 0.628
IL1R1
Interleukin 1 receptor type 1.
   
 
0.595
IL1RL2
Interleukin 1 receptor like 2.
   
 
0.591
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.