Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLE1TLE family member 1, transcriptional corepressor. (702 aa)    
Predicted Functional Partners:
TLE3
TLE family member 3, transcriptional corepressor.
   
 0.999
LEF1
Lymphoid enhancer binding factor 1.
    
 0.992
HDAC1
Histone deacetylase 1.
    
 0.984
TLE2
TLE family member 2, transcriptional corepressor.
   
  0.980
TLE4
TLE family member 4, transcriptional corepressor.
   
  0.980
TBX20
T-box transcription factor 20.
    
 
 0.967
TCF7L1
Transcription factor 7 like 1.
    
 0.965
TCF7
Transcription factor 7.
    
 0.964
ENSCAPP00000017363
annotation not available
    
 0.964
HDAC2
Histone deacetylase 2.
    
 0.963
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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