Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGFG1ArfGAP with FG repeats 1. (414 aa)    
Predicted Functional Partners:
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 0.967
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
    
 0.937
RAB1A
RAB1A, member RAS oncogene family.
   
  
 0.896
TMPRSS12
Transmembrane serine protease 12.
      
 0.766
ITSN2
Intersectin 2.
    
 0.751
BTBD18
BTB domain containing 18.
      
 0.741
RAB2A
RAB2A, member RAS oncogene family.
      
 0.689
FAM126B
Family with sequence similarity 126 member B.
      
 0.687
RAB3A
RAB3A, member RAS oncogene family.
      
 0.683
AP1B1
Adaptor related protein complex 1 subunit beta 1.
    
 0.669
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (20%) [HD]