Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APLP2Amyloid beta precursor like protein 2. (735 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
   
  0.993
APBB2
Amyloid beta precursor protein binding family B member 2.
    
 0.987
ENSCAPP00000016356
annotation not available
    
 0.977
ENSCAPP00000017143
annotation not available
    
 0.977
APBB3
Amyloid beta precursor protein binding family B member 3.
    
 0.953
TTR
Transthyretin.
    
 0.947
NAE1
NEDD8 activating enzyme E1 subunit 1.
    
 0.943
SORL1
Sortilin related receptor 1.
    
 0.935
CLU
Clusterin.
   
 0.918
PRNP
Prion protein.
   
 0.915
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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