Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2521 aa)    
Predicted Functional Partners:
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
   
 0.997
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
   
 0.981
HTT
Huntingtin.
    
 0.965
PLCB4
Phospholipase C beta 4.
    
 0.961
PLCB2
Phospholipase C beta 2.
    
 0.959
PLCB1
Phospholipase C beta 1.
   
 0.954
PLCG2
Phospholipase C gamma 2.
     
 0.944
MRVI1
Murine retrovirus integration site 1 homolog.
    
 0.944
PLCB3
Phospholipase C beta 3.
    
 0.936
ENSCAPP00000017763
annotation not available
    
 0.936
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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