Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAV1Salvador family WW domain containing protein 1. (266 aa)    
Predicted Functional Partners:
LATS2
Large tumor suppressor kinase 2.
    
 0.998
STK3
Serine/threonine kinase 3.
    
 0.998
STK4
Serine/threonine kinase 4.
    
 0.996
LATS1
Large tumor suppressor kinase 1.
    
 0.995
LIMD1
LIM domains containing 1.
   
 0.985
MOB1A
MOB kinase activator 1A.
    
 0.974
RASSF1
Ras association domain family member 1.
    
 
 0.970
MOB1B
MOB kinase activator 1B.
     
 0.964
AMOTL1
Angiomotin like 1.
    
 0.949
NF2
Neurofibromin 2.
    
 0.942
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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