SAV1 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SAV1

Salvador family WW domain containing protein 1. (266 aa)

Predicted Functional Partners:

STK3

0.992

STK4

0.985

LATS1

0.963

LATS2

0.962

ENSCAPP00000017509

0.940

LIMD1

0.912

MOB1A

0.881

NF2

0.869

MOB1B

0.851

WWTR1

0.809

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000017509	LATS1	ENSCAPP00000017509	ENSCAPP00000011268	annotation not available	Large tumor suppressor kinase 1.	0.959
ENSCAPP00000017509	LATS2	ENSCAPP00000017509	ENSCAPP00000015437	annotation not available	Large tumor suppressor kinase 2.	0.934
ENSCAPP00000017509	LIMD1	ENSCAPP00000017509	ENSCAPP00000011499	annotation not available	LIM domains containing 1.	0.819
ENSCAPP00000017509	SAV1	ENSCAPP00000017509	ENSCAPP00000005660	annotation not available	Salvador family WW domain containing protein 1.	0.940
LATS1	ENSCAPP00000017509	ENSCAPP00000011268	ENSCAPP00000017509	Large tumor suppressor kinase 1.	annotation not available	0.959
LATS1	LATS2	ENSCAPP00000011268	ENSCAPP00000015437	Large tumor suppressor kinase 1.	Large tumor suppressor kinase 2.	0.927
LATS1	LIMD1	ENSCAPP00000011268	ENSCAPP00000011499	Large tumor suppressor kinase 1.	LIM domains containing 1.	0.959
LATS1	MOB1A	ENSCAPP00000011268	ENSCAPP00000002239	Large tumor suppressor kinase 1.	MOB kinase activator 1A.	0.989
LATS1	MOB1B	ENSCAPP00000011268	ENSCAPP00000004717	Large tumor suppressor kinase 1.	MOB kinase activator 1B.	0.990
LATS1	NF2	ENSCAPP00000011268	ENSCAPP00000009343	Large tumor suppressor kinase 1.	Neurofibromin 2.	0.968
LATS1	SAV1	ENSCAPP00000011268	ENSCAPP00000005660	Large tumor suppressor kinase 1.	Salvador family WW domain containing protein 1.	0.963
LATS1	STK3	ENSCAPP00000011268	ENSCAPP00000017281	Large tumor suppressor kinase 1.	Serine/threonine kinase 3.	0.977
LATS1	STK4	ENSCAPP00000011268	ENSCAPP00000015571	Large tumor suppressor kinase 1.	Serine/threonine kinase 4.	0.930
LATS1	WWTR1	ENSCAPP00000011268	ENSCAPP00000012523	Large tumor suppressor kinase 1.	WW domain containing transcription regulator 1.	0.951
LATS2	ENSCAPP00000017509	ENSCAPP00000015437	ENSCAPP00000017509	Large tumor suppressor kinase 2.	annotation not available	0.934
LATS2	LATS1	ENSCAPP00000015437	ENSCAPP00000011268	Large tumor suppressor kinase 2.	Large tumor suppressor kinase 1.	0.927
LATS2	LIMD1	ENSCAPP00000015437	ENSCAPP00000011499	Large tumor suppressor kinase 2.	LIM domains containing 1.	0.940
LATS2	MOB1A	ENSCAPP00000015437	ENSCAPP00000002239	Large tumor suppressor kinase 2.	MOB kinase activator 1A.	0.977
LATS2	MOB1B	ENSCAPP00000015437	ENSCAPP00000004717	Large tumor suppressor kinase 2.	MOB kinase activator 1B.	0.972
LATS2	NF2	ENSCAPP00000015437	ENSCAPP00000009343	Large tumor suppressor kinase 2.	Neurofibromin 2.	0.968