Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
RUBCNRubicon autophagy regulator. (965 aa)    
Predicted Functional Partners:
PIK3R4
Phosphoinositide-3-kinase regulatory subunit 4.
    
 
 0.992
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 
 0.983
ENSCAPP00000005383
annotation not available
    
 
 0.972
RAB7A
RAB7A, member RAS oncogene family.
    
 0.966
EGFR
Epidermal growth factor receptor.
    
 
 0.951
ENSCAPP00000010142
annotation not available
    
 0.917
GABARAPL2
GABA type A receptor associated protein like 2.
    
 0.895
ENSCAPP00000017351
annotation not available
    
 0.892
RAB9A
RAB9A, member RAS oncogene family.
   
 0.891
ATG14
Autophagy related 14.
    
 
 0.890
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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