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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM2D2TM2 domain containing 2. (138 aa)    
Predicted Functional Partners:
PIGA
Phosphatidylinositol glycan anchor biosynthesis class A.
     
 0.810
PIGC
Phosphatidylinositol glycan anchor biosynthesis class C.
     
 0.781
PIGL
Phosphatidylinositol glycan anchor biosynthesis class L.
     
 0.729
ENSCAPP00000002852
annotation not available
   
 
  0.640
TM2D1
TM2 domain containing 1.
   
  
 0.582
ENSCAPP00000013045
annotation not available
   
  
 0.566
NHLRC2
NHL repeat containing 2.
      
 0.565
NPRL2
NPR2 like, GATOR1 complex subunit.
   
  
 0.564
FAM110A
Family with sequence similarity 110 member A.
      
 0.562
PLEKHA2
Pleckstrin homology domain containing A2.
      
 0.546
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.