CIITA protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

CIITA

Class II major histocompatibility complex transactivator. (962 aa)

Predicted Functional Partners:

ENSCAPP00000003646

0.999

RFXANK

0.995

STAT1

0.970

ENSCAPP00000002391

0.945

NFYA

0.945

NFYB

0.939

PSMC5

0.925

CREB1

0.921

HDAC2

0.916

ENSCAPP00000009603

0.911

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CIITA	CREB1	ENSCAPP00000005762	ENSCAPP00000008122	Class II major histocompatibility complex transactivator.	cAMP responsive element binding protein 1.	0.921
CIITA	ENSCAPP00000002391	ENSCAPP00000005762	ENSCAPP00000002391	Class II major histocompatibility complex transactivator.	annotation not available	0.945
CIITA	ENSCAPP00000003646	ENSCAPP00000005762	ENSCAPP00000003646	Class II major histocompatibility complex transactivator.	annotation not available	0.999
CIITA	ENSCAPP00000009603	ENSCAPP00000005762	ENSCAPP00000009603	Class II major histocompatibility complex transactivator.	annotation not available	0.911
CIITA	HDAC2	ENSCAPP00000005762	ENSCAPP00000016491	Class II major histocompatibility complex transactivator.	Histone deacetylase 2.	0.916
CIITA	NFYA	ENSCAPP00000005762	ENSCAPP00000005088	Class II major histocompatibility complex transactivator.	Nuclear transcription factor Y subunit alpha.	0.945
CIITA	NFYB	ENSCAPP00000005762	ENSCAPP00000013824	Class II major histocompatibility complex transactivator.	Nuclear transcription factor Y subunit beta.	0.939
CIITA	PSMC5	ENSCAPP00000005762	ENSCAPP00000011918	Class II major histocompatibility complex transactivator.	Proteasome 26S subunit, ATPase 5.	0.925
CIITA	RFXANK	ENSCAPP00000005762	ENSCAPP00000006621	Class II major histocompatibility complex transactivator.	Regulatory factor X associated ankyrin containing protein.	0.995
CIITA	STAT1	ENSCAPP00000005762	ENSCAPP00000017991	Class II major histocompatibility complex transactivator.	Signal transducer and activator of transcription 1.	0.970
CREB1	CIITA	ENSCAPP00000008122	ENSCAPP00000005762	cAMP responsive element binding protein 1.	Class II major histocompatibility complex transactivator.	0.921
CREB1	ENSCAPP00000003646	ENSCAPP00000008122	ENSCAPP00000003646	cAMP responsive element binding protein 1.	annotation not available	0.477
CREB1	ENSCAPP00000009603	ENSCAPP00000008122	ENSCAPP00000009603	cAMP responsive element binding protein 1.	annotation not available	0.407
CREB1	HDAC2	ENSCAPP00000008122	ENSCAPP00000016491	cAMP responsive element binding protein 1.	Histone deacetylase 2.	0.841
CREB1	NFYA	ENSCAPP00000008122	ENSCAPP00000005088	cAMP responsive element binding protein 1.	Nuclear transcription factor Y subunit alpha.	0.462
CREB1	STAT1	ENSCAPP00000008122	ENSCAPP00000017991	cAMP responsive element binding protein 1.	Signal transducer and activator of transcription 1.	0.753
ENSCAPP00000002391	CIITA	ENSCAPP00000002391	ENSCAPP00000005762	annotation not available	Class II major histocompatibility complex transactivator.	0.945
ENSCAPP00000002391	ENSCAPP00000003646	ENSCAPP00000002391	ENSCAPP00000003646	annotation not available	annotation not available	0.524
ENSCAPP00000002391	NFYA	ENSCAPP00000002391	ENSCAPP00000005088	annotation not available	Nuclear transcription factor Y subunit alpha.	0.999
ENSCAPP00000002391	NFYB	ENSCAPP00000002391	ENSCAPP00000013824	annotation not available	Nuclear transcription factor Y subunit beta.	0.999