Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KYNUKynureninase. (310 aa)    
Predicted Functional Partners:
TDO2
Tryptophan 2,3-dioxygenase.
  
 
 0.993
KMO
Kynurenine 3-monooxygenase.
 
 
 0.991
HAAO
3-hydroxyanthranilate 3,4-dioxygenase.
  
 
 0.990
IDO1
Indoleamine 2,3-dioxygenase 1.
   
 0.975
AFMID
Arylformamidase.
  
 
 0.973
ENSCAPP00000003178
annotation not available
   
 
 0.963
ENSCAPP00000013365
annotation not available
   
 
 0.962
KYAT3
Kynurenine aminotransferase 3.
   
 
 0.951
CAT
Catalase.
   
 
 0.919
ALDH3A2
Aldehyde dehydrogenase 3 family member A2.
  
  
 0.875
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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