FXR1 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FXR1

FMR1 autosomal homolog 1. (656 aa)

Predicted Functional Partners:

FXR2

0.982

CYFIP1

0.978

FMR1

0.964

CYFIP2

0.955

PKP3

0.858

AGO2

0.822

AGO1

0.821

ENSCAPP00000009222

0.772

DDX20

0.760

G3BP1

0.737

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO1	AGO2	ENSCAPP00000008559	ENSCAPP00000013010	Argonaute RISC component 1.	Argonaute RISC catalytic component 2.	0.993
AGO1	DDX20	ENSCAPP00000008559	ENSCAPP00000017863	Argonaute RISC component 1.	DEAD-box helicase 20.	0.732
AGO1	FMR1	ENSCAPP00000008559	ENSCAPP00000006450	Argonaute RISC component 1.	FMRP translational regulator 1.	0.820
AGO1	FXR1	ENSCAPP00000008559	ENSCAPP00000005794	Argonaute RISC component 1.	FMR1 autosomal homolog 1.	0.821
AGO1	FXR2	ENSCAPP00000008559	ENSCAPP00000003681	Argonaute RISC component 1.	FMR1 autosomal homolog 2.	0.737
AGO1	G3BP1	ENSCAPP00000008559	ENSCAPP00000000689	Argonaute RISC component 1.	G3BP stress granule assembly factor 1.	0.414
AGO2	AGO1	ENSCAPP00000013010	ENSCAPP00000008559	Argonaute RISC catalytic component 2.	Argonaute RISC component 1.	0.993
AGO2	CYFIP1	ENSCAPP00000013010	ENSCAPP00000013850	Argonaute RISC catalytic component 2.	Cytoplasmic FMR1 interacting protein 1.	0.912
AGO2	DDX20	ENSCAPP00000013010	ENSCAPP00000017863	Argonaute RISC catalytic component 2.	DEAD-box helicase 20.	0.784
AGO2	FMR1	ENSCAPP00000013010	ENSCAPP00000006450	Argonaute RISC catalytic component 2.	FMRP translational regulator 1.	0.899
AGO2	FXR1	ENSCAPP00000013010	ENSCAPP00000005794	Argonaute RISC catalytic component 2.	FMR1 autosomal homolog 1.	0.822
AGO2	FXR2	ENSCAPP00000013010	ENSCAPP00000003681	Argonaute RISC catalytic component 2.	FMR1 autosomal homolog 2.	0.815
AGO2	G3BP1	ENSCAPP00000013010	ENSCAPP00000000689	Argonaute RISC catalytic component 2.	G3BP stress granule assembly factor 1.	0.526
CYFIP1	AGO2	ENSCAPP00000013850	ENSCAPP00000013010	Cytoplasmic FMR1 interacting protein 1.	Argonaute RISC catalytic component 2.	0.912
CYFIP1	CYFIP2	ENSCAPP00000013850	ENSCAPP00000008353	Cytoplasmic FMR1 interacting protein 1.	Cytoplasmic FMR1 interacting protein 2.	0.957
CYFIP1	FMR1	ENSCAPP00000013850	ENSCAPP00000006450	Cytoplasmic FMR1 interacting protein 1.	FMRP translational regulator 1.	0.959
CYFIP1	FXR1	ENSCAPP00000013850	ENSCAPP00000005794	Cytoplasmic FMR1 interacting protein 1.	FMR1 autosomal homolog 1.	0.978
CYFIP1	FXR2	ENSCAPP00000013850	ENSCAPP00000003681	Cytoplasmic FMR1 interacting protein 1.	FMR1 autosomal homolog 2.	0.954
CYFIP2	CYFIP1	ENSCAPP00000008353	ENSCAPP00000013850	Cytoplasmic FMR1 interacting protein 2.	Cytoplasmic FMR1 interacting protein 1.	0.957
CYFIP2	FMR1	ENSCAPP00000008353	ENSCAPP00000006450	Cytoplasmic FMR1 interacting protein 2.	FMRP translational regulator 1.	0.955