Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA8Pleckstrin homology domain containing A8. (386 aa)    
Predicted Functional Partners:
ARF1
ADP ribosylation factor 1.
    
 0.906
MNAT1
MNAT1 component of CDK activating kinase.
      
 0.795
TMTC4
Transmembrane O-mannosyltransferase targeting cadherins 4.
      
 0.738
ENSCAPP00000008335
annotation not available
    
 0.729
TRIP4
Thyroid hormone receptor interactor 4.
      
 0.722
ARL6
ADP ribosylation factor like GTPase 6.
    
 0.689
CEL
Carboxyl ester lipase.
      
 0.684
GPATCH3
G-patch domain containing 3.
      
 0.680
RSPRY1
Ring finger and SPRY domain containing 1.
      
 0.662
MPEG1
Macrophage expressed 1.
      
 0.661
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: high (90%) [HD]