Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLK7Kallikrein related peptidase 7. (246 aa)    
Predicted Functional Partners:
KLK8
Kallikrein related peptidase 8.
   
    0.839
ENSCAPP00000015753
annotation not available
    
 0.763
ANKRD1
Ankyrin repeat domain 1.
    
 
 0.715
SERPINA12
Serpin family A member 12.
  
 0.686
CDSN
Corneodesmosin.
   
 
 0.670
DSG1
Desmoglein 1.
   
 
 0.650
CDH1
Cadherin 1.
   
 
 0.625
CDH3
Cadherin 3.
   
 
 0.614
TMEM150A
Transmembrane protein 150A.
      
 0.602
PGC
Progastricsin.
    
 0.599
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]