close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLE3DNA polymerase epsilon 3, accessory subunit. (96 aa)    
Predicted Functional Partners:
POLE
DNA polymerase epsilon, catalytic subunit.
   
 0.999
POLE2
DNA polymerase epsilon 2, accessory subunit.
    
 0.999
BAZ1A
Bromodomain adjacent to zinc finger domain 1A.
    
 0.997
CHRAC1
Chromatin accessibility complex subunit 1.
    
 0.997
DR1
Down-regulator of transcription 1.
   
 0.995
POLD1
DNA polymerase delta 1, catalytic subunit.
   
 0.992
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
   
 0.992
SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1.
    
 0.984
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.
    
 0.984
WRN
WRN RecQ like helicase.
    
 0.981
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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