HESX1 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HESX1

HESX homeobox 1. (185 aa)

Predicted Functional Partners:

LDB2

0.684

LDB1

0.684

SRF

0.615

LHX3

0.614

POU1F1

0.598

ENSCAPP00000007831

0.552

TCF3

0.547

ZPBP

0.546

ENSCAPP00000011786

0.542

TCF4

0.542

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000007831	HESX1	ENSCAPP00000007831	ENSCAPP00000005837	annotation not available	HESX homeobox 1.	0.552
ENSCAPP00000007831	LDB1	ENSCAPP00000007831	ENSCAPP00000007918	annotation not available	LIM domain binding 1.	0.853
ENSCAPP00000007831	LDB2	ENSCAPP00000007831	ENSCAPP00000007810	annotation not available	LIM domain binding 2.	0.709
ENSCAPP00000007831	LHX3	ENSCAPP00000007831	ENSCAPP00000017416	annotation not available	LIM homeobox 3.	0.522
ENSCAPP00000007831	POU1F1	ENSCAPP00000007831	ENSCAPP00000016106	annotation not available	POU class 1 homeobox 1.	0.629
ENSCAPP00000011786	HESX1	ENSCAPP00000011786	ENSCAPP00000005837	annotation not available	HESX homeobox 1.	0.542
ENSCAPP00000011786	LDB1	ENSCAPP00000011786	ENSCAPP00000007918	annotation not available	LIM domain binding 1.	0.914
ENSCAPP00000011786	LDB2	ENSCAPP00000011786	ENSCAPP00000007810	annotation not available	LIM domain binding 2.	0.721
ENSCAPP00000011786	TCF3	ENSCAPP00000011786	ENSCAPP00000002686	annotation not available	Transcription factor 3.	0.633
HESX1	ENSCAPP00000007831	ENSCAPP00000005837	ENSCAPP00000007831	HESX homeobox 1.	annotation not available	0.552
HESX1	ENSCAPP00000011786	ENSCAPP00000005837	ENSCAPP00000011786	HESX homeobox 1.	annotation not available	0.542
HESX1	LDB1	ENSCAPP00000005837	ENSCAPP00000007918	HESX homeobox 1.	LIM domain binding 1.	0.684
HESX1	LDB2	ENSCAPP00000005837	ENSCAPP00000007810	HESX homeobox 1.	LIM domain binding 2.	0.684
HESX1	LHX3	ENSCAPP00000005837	ENSCAPP00000017416	HESX homeobox 1.	LIM homeobox 3.	0.614
HESX1	POU1F1	ENSCAPP00000005837	ENSCAPP00000016106	HESX homeobox 1.	POU class 1 homeobox 1.	0.598
HESX1	SRF	ENSCAPP00000005837	ENSCAPP00000004937	HESX homeobox 1.	Serum response factor.	0.615
HESX1	TCF3	ENSCAPP00000005837	ENSCAPP00000002686	HESX homeobox 1.	Transcription factor 3.	0.547
HESX1	TCF4	ENSCAPP00000005837	ENSCAPP00000015336	HESX homeobox 1.	Transcription factor 4.	0.542
HESX1	ZPBP	ENSCAPP00000005837	ENSCAPP00000000645	HESX homeobox 1.	Zona pellucida binding protein.	0.546
LDB1	ENSCAPP00000007831	ENSCAPP00000007918	ENSCAPP00000007831	LIM domain binding 1.	annotation not available	0.853