Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPM2AEPM2A glucan phosphatase, laforin. (230 aa)    
Predicted Functional Partners:
PPP1R3B
Protein phosphatase 1 regulatory subunit 3B.
   
 0.926
ENSCAPP00000008506
annotation not available
   
  0.828
ENSCAPP00000009570
annotation not available
   
  0.828
GYS1
Glycogen synthase 1.
    
 0.818
PPP1R3A
Protein phosphatase 1 regulatory subunit 3A.
    
 0.672
NFU1
NFU1 iron-sulfur cluster scaffold.
    
 
 0.671
GYS2
Glycogen synthase 2.
    
 0.644
BMT2
Base methyltransferase of 25S rRNA 2 homolog.
    
 0.633
PYGB
Glycogen phosphorylase B.
    
 
 0.630
AGL
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase.
    
 
 0.630
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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