Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPRKProtein tyrosine phosphatase receptor type K. (1362 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
  0.885
CTNND1
Catenin delta 1.
    
 0.830
ARVCF
ARVCF delta catenin family member.
    
 0.830
JUP
Junction plakoglobin.
    
  0.817
PTPRM
Protein tyrosine phosphatase receptor type M.
    
 0.812
ENSCAPP00000001903
annotation not available
    
 0.812
PTPRU
Protein tyrosine phosphatase receptor type U.
    
 0.736
ENSCAPP00000005516
annotation not available
    
 0.712
PKP4
Plakophilin 4.
    
 0.712
TNC
Tenascin C.
    
  0.617
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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