Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SHANK3SH3 and multiple ankyrin repeat domains 3. (1482 aa)    
Predicted Functional Partners:
SHANK1
SH3 and multiple ankyrin repeat domains 1.
    
 0.996
HOMER1
Homer scaffold protein 1.
    
 0.988
DLGAP2
DLG associated protein 2.
   
 0.980
LZTS3
Leucine zipper tumor suppressor family member 3.
     
 0.976
DLGAP1
DLG associated protein 1.
   
 0.963
DLGAP3
DLG associated protein 3.
   
 0.962
ENSCAPP00000015905
annotation not available
   
 0.948
ENSCAPP00000012309
annotation not available
   
 0.944
SHANK2
SH3 and multiple ankyrin repeat domains 2.
   
 0.943
SYNGAP1
Synaptic Ras GTPase activating protein 1.
   
 
 0.897
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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