Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F8E2F transcription factor 8. (841 aa)    
Predicted Functional Partners:
E2F7
E2F transcription factor 7.
   
 0.985
ENSCAPP00000012564
annotation not available
   
  
 0.947
TTK
TTK protein kinase.
   
  
 0.917
KIF15
Kinesin family member 15.
   
  
 0.908
TOP2A
DNA topoisomerase II alpha.
   
  
 0.874
CCNA2
Cyclin A2.
   
 
 0.873
KIF20A
Kinesin family member 20A.
   
  
 0.868
ENSCAPP00000014267
annotation not available
   
  
 0.856
KIF2C
Kinesin family member 2C.
   
  
 0.845
CDCA8
Cell division cycle associated 8.
   
  
 0.844
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: medium (44%) [HD]