Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAB8ARAB8A, member RAS oncogene family. (117 aa)    
Predicted Functional Partners:
RAB8B
RAB8B, member RAS oncogene family.
   
  0.999
ENSCAPP00000001732
annotation not available
    
 0.996
RAB10
RAB10, member RAS oncogene family.
   
  0.987
C9orf72
C9orf72-SMCR8 complex subunit.
    
 0.984
ENSCAPP00000015096
annotation not available
   
 0.984
RABIF
RAB interacting factor.
    
 
 0.982
RAB1A
RAB1A, member RAS oncogene family.
   
  0.976
CEP290
Centrosomal protein 290.
    
 0.976
OCRL
OCRL inositol polyphosphate-5-phosphatase.
    
 
 0.967
TBC1D1
TBC1 domain family member 1.
    
 0.961
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.