NFE2 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NFE2

Nuclear factor, erythroid 2. (391 aa)

Predicted Functional Partners:

MAFG

0.954

MAFK

0.917

NFE2L1

0.906

NFE2L2

0.871

DDIT3

0.846

EIF2AK3

0.844

ENSCAPP00000016515

0.832

EIF2AK4

0.805

KEAP1

0.786

KLHL17

0.786

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDIT3	EIF2AK3	ENSCAPP00000005759	ENSCAPP00000013660	DNA damage inducible transcript 3.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.532
DDIT3	ENSCAPP00000016515	ENSCAPP00000005759	ENSCAPP00000016515	DNA damage inducible transcript 3.	annotation not available	0.415
DDIT3	NFE2	ENSCAPP00000005759	ENSCAPP00000005935	DNA damage inducible transcript 3.	Nuclear factor, erythroid 2.	0.846
DDIT3	NFE2L1	ENSCAPP00000005759	ENSCAPP00000009623	DNA damage inducible transcript 3.	Nuclear factor, erythroid 2 like 1.	0.759
DDIT3	NFE2L2	ENSCAPP00000005759	ENSCAPP00000001397	DNA damage inducible transcript 3.	Nuclear factor, erythroid 2 like 2.	0.936
EIF2AK3	DDIT3	ENSCAPP00000013660	ENSCAPP00000005759	Eukaryotic translation initiation factor 2 alpha kinase 3.	DNA damage inducible transcript 3.	0.532
EIF2AK3	EIF2AK4	ENSCAPP00000013660	ENSCAPP00000000658	Eukaryotic translation initiation factor 2 alpha kinase 3.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.862
EIF2AK3	ENSCAPP00000016515	ENSCAPP00000013660	ENSCAPP00000016515	Eukaryotic translation initiation factor 2 alpha kinase 3.	annotation not available	0.806
EIF2AK3	NFE2	ENSCAPP00000013660	ENSCAPP00000005935	Eukaryotic translation initiation factor 2 alpha kinase 3.	Nuclear factor, erythroid 2.	0.844
EIF2AK3	NFE2L1	ENSCAPP00000013660	ENSCAPP00000009623	Eukaryotic translation initiation factor 2 alpha kinase 3.	Nuclear factor, erythroid 2 like 1.	0.770
EIF2AK3	NFE2L2	ENSCAPP00000013660	ENSCAPP00000001397	Eukaryotic translation initiation factor 2 alpha kinase 3.	Nuclear factor, erythroid 2 like 2.	0.943
EIF2AK4	EIF2AK3	ENSCAPP00000000658	ENSCAPP00000013660	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.862
EIF2AK4	ENSCAPP00000016515	ENSCAPP00000000658	ENSCAPP00000016515	Eukaryotic translation initiation factor 2 alpha kinase 4.	annotation not available	0.836
EIF2AK4	NFE2	ENSCAPP00000000658	ENSCAPP00000005935	Eukaryotic translation initiation factor 2 alpha kinase 4.	Nuclear factor, erythroid 2.	0.805
EIF2AK4	NFE2L1	ENSCAPP00000000658	ENSCAPP00000009623	Eukaryotic translation initiation factor 2 alpha kinase 4.	Nuclear factor, erythroid 2 like 1.	0.696
EIF2AK4	NFE2L2	ENSCAPP00000000658	ENSCAPP00000001397	Eukaryotic translation initiation factor 2 alpha kinase 4.	Nuclear factor, erythroid 2 like 2.	0.911
ENSCAPP00000016515	DDIT3	ENSCAPP00000016515	ENSCAPP00000005759	annotation not available	DNA damage inducible transcript 3.	0.415
ENSCAPP00000016515	EIF2AK3	ENSCAPP00000016515	ENSCAPP00000013660	annotation not available	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.806
ENSCAPP00000016515	EIF2AK4	ENSCAPP00000016515	ENSCAPP00000000658	annotation not available	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.836
ENSCAPP00000016515	NFE2	ENSCAPP00000016515	ENSCAPP00000005935	annotation not available	Nuclear factor, erythroid 2.	0.832