SFXN2 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

SFXN2

Sideroflexin 2. (319 aa)

Predicted Functional Partners:

SPG7

0.838

ENSCAPP00000005436

0.620

ENSCAPP00000006409

0.620

RAB25

0.612

RALGPS1

0.569

MTBP

0.524

TREH

0.518

IMMT

0.485

ENSCAPP00000003131

0.469

RNF14

0.454

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000003131	IMMT	ENSCAPP00000003131	ENSCAPP00000010065	annotation not available	Inner membrane mitochondrial protein.	0.755
ENSCAPP00000003131	SFXN2	ENSCAPP00000003131	ENSCAPP00000005976	annotation not available	Sideroflexin 2.	0.469
ENSCAPP00000005436	ENSCAPP00000006409	ENSCAPP00000005436	ENSCAPP00000006409	annotation not available	annotation not available	0.864
ENSCAPP00000005436	RAB25	ENSCAPP00000005436	ENSCAPP00000003390	annotation not available	RAB25, member RAS oncogene family.	0.581
ENSCAPP00000005436	SFXN2	ENSCAPP00000005436	ENSCAPP00000005976	annotation not available	Sideroflexin 2.	0.620
ENSCAPP00000006409	ENSCAPP00000005436	ENSCAPP00000006409	ENSCAPP00000005436	annotation not available	annotation not available	0.864
ENSCAPP00000006409	RAB25	ENSCAPP00000006409	ENSCAPP00000003390	annotation not available	RAB25, member RAS oncogene family.	0.581
ENSCAPP00000006409	SFXN2	ENSCAPP00000006409	ENSCAPP00000005976	annotation not available	Sideroflexin 2.	0.620
IMMT	ENSCAPP00000003131	ENSCAPP00000010065	ENSCAPP00000003131	Inner membrane mitochondrial protein.	annotation not available	0.755
IMMT	SFXN2	ENSCAPP00000010065	ENSCAPP00000005976	Inner membrane mitochondrial protein.	Sideroflexin 2.	0.485
IMMT	SPG7	ENSCAPP00000010065	ENSCAPP00000017071	Inner membrane mitochondrial protein.	SPG7 matrix AAA peptidase subunit, paraplegin.	0.582
MTBP	RALGPS1	ENSCAPP00000015879	ENSCAPP00000005242	MDM2 binding protein.	Ral GEF with PH domain and SH3 binding motif 1.	0.573
MTBP	RNF14	ENSCAPP00000015879	ENSCAPP00000001637	MDM2 binding protein.	Ring finger protein 14.	0.410
MTBP	SFXN2	ENSCAPP00000015879	ENSCAPP00000005976	MDM2 binding protein.	Sideroflexin 2.	0.524
RAB25	ENSCAPP00000005436	ENSCAPP00000003390	ENSCAPP00000005436	RAB25, member RAS oncogene family.	annotation not available	0.581
RAB25	ENSCAPP00000006409	ENSCAPP00000003390	ENSCAPP00000006409	RAB25, member RAS oncogene family.	annotation not available	0.581
RAB25	SFXN2	ENSCAPP00000003390	ENSCAPP00000005976	RAB25, member RAS oncogene family.	Sideroflexin 2.	0.612
RALGPS1	MTBP	ENSCAPP00000005242	ENSCAPP00000015879	Ral GEF with PH domain and SH3 binding motif 1.	MDM2 binding protein.	0.573
RALGPS1	RNF14	ENSCAPP00000005242	ENSCAPP00000001637	Ral GEF with PH domain and SH3 binding motif 1.	Ring finger protein 14.	0.441
RALGPS1	SFXN2	ENSCAPP00000005242	ENSCAPP00000005976	Ral GEF with PH domain and SH3 binding motif 1.	Sideroflexin 2.	0.569