Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM4SF5Transmembrane 4 L six family member 5. (221 aa)    
Predicted Functional Partners:
C11orf54
Chromosome 11 open reading frame 54.
      
 0.689
LRCH4
Leucine rich repeats and calponin homology domain containing 4.
      
 0.658
SLC38A9
Solute carrier family 38 member 9.
    
 
 0.612
GLYCTK
Glycerate kinase.
      
 0.605
VSTM5
V-set and transmembrane domain containing 5.
      
 0.601
TSPAN1
Tetraspanin 1.
      
 0.571
CDHR1
Cadherin related family member 1.
   
  
 0.571
SMCO4
Single-pass membrane protein with coiled-coil domains 4.
      
 0.551
TM4SF20
Transmembrane 4 L six family member 20.
   
  
 0.492
ENSCAPP00000004818
annotation not available
      
 0.454
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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