Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POLBDNA polymerase beta. (419 aa)    
Predicted Functional Partners:
PNKP
Polynucleotide kinase 3'-phosphatase.
    
 0.998
LIG3
DNA ligase 3.
   
 0.997
XRCC1
X-ray repair cross complementing 1.
    
 0.997
APEX1
Apurinic/apyrimidinic endodeoxyribonuclease 1.
    
 0.994
XPC
XPC complex subunit, DNA damage recognition and repair factor.
    
 
 0.981
TDP1
tyrosyl-DNA phosphodiesterase 1.
    
 
 0.979
FEN1
Flap structure-specific endonuclease 1.
   
 0.978
ENSCAPP00000009733
annotation not available
    
 0.972
ENSCAPP00000012367
annotation not available
    
 0.972
ENSCAPP00000000297
annotation not available
   
 0.970
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (22%) [HD]