Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRPV6Transient receptor potential cation channel subfamily V member 6. (684 aa)    
Predicted Functional Partners:
WNK4
WNK lysine deficient protein kinase 4.
    
 0.948
PRKCG
Protein kinase C gamma.
    
 0.875
WNK2
WNK lysine deficient protein kinase 2.
    
  0.863
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
    
 0.852
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
    
 0.852
CNTD1
Cyclin N-terminal domain containing 1.
    
 0.849
PRKCA
Protein kinase C alpha.
    
 0.844
PRKCB
Protein kinase C beta.
    
 0.844
TRPM2
Transient receptor potential cation channel subfamily M member 2.
     
 0.843
CALML3
Calmodulin like 3.
    
 0.797
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.