MTAP protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MTAP

Methylthioadenosine phosphorylase. (209 aa)

Predicted Functional Partners:

SRM

0.928

MRI1

0.899

ENSCAPP00000002499

0.878

ENSCAPP00000007765

0.878

ENSCAPP00000018695

0.865

EPHX2

0.849

APRT

0.831

ENKUR

0.820

UPP1

0.728

UPP2

0.728

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APRT	ENKUR	ENSCAPP00000008600	ENSCAPP00000003809	Adenine phosphoribosyltransferase.	Enkurin, TRPC channel interacting protein.	0.847
APRT	ENSCAPP00000018695	ENSCAPP00000008600	ENSCAPP00000018695	Adenine phosphoribosyltransferase.	annotation not available	0.926
APRT	EPHX2	ENSCAPP00000008600	ENSCAPP00000005800	Adenine phosphoribosyltransferase.	Epoxide hydrolase 2.	0.846
APRT	MRI1	ENSCAPP00000008600	ENSCAPP00000015339	Adenine phosphoribosyltransferase.	Methylthioribose-1-phosphate isomerase 1.	0.497
APRT	MTAP	ENSCAPP00000008600	ENSCAPP00000006046	Adenine phosphoribosyltransferase.	Methylthioadenosine phosphorylase.	0.831
APRT	SRM	ENSCAPP00000008600	ENSCAPP00000017599	Adenine phosphoribosyltransferase.	Spermidine synthase.	0.433
APRT	UPP1	ENSCAPP00000008600	ENSCAPP00000009671	Adenine phosphoribosyltransferase.	Uridine phosphorylase 1.	0.828
APRT	UPP2	ENSCAPP00000008600	ENSCAPP00000013452	Adenine phosphoribosyltransferase.	Uridine phosphorylase 2.	0.864
ENKUR	APRT	ENSCAPP00000003809	ENSCAPP00000008600	Enkurin, TRPC channel interacting protein.	Adenine phosphoribosyltransferase.	0.847
ENKUR	ENSCAPP00000018695	ENSCAPP00000003809	ENSCAPP00000018695	Enkurin, TRPC channel interacting protein.	annotation not available	0.853
ENKUR	EPHX2	ENSCAPP00000003809	ENSCAPP00000005800	Enkurin, TRPC channel interacting protein.	Epoxide hydrolase 2.	0.843
ENKUR	MTAP	ENSCAPP00000003809	ENSCAPP00000006046	Enkurin, TRPC channel interacting protein.	Methylthioadenosine phosphorylase.	0.820
ENKUR	UPP1	ENSCAPP00000003809	ENSCAPP00000009671	Enkurin, TRPC channel interacting protein.	Uridine phosphorylase 1.	0.741
ENKUR	UPP2	ENSCAPP00000003809	ENSCAPP00000013452	Enkurin, TRPC channel interacting protein.	Uridine phosphorylase 2.	0.741
ENSCAPP00000002499	ENSCAPP00000018695	ENSCAPP00000002499	ENSCAPP00000018695	annotation not available	annotation not available	0.855
ENSCAPP00000002499	MTAP	ENSCAPP00000002499	ENSCAPP00000006046	annotation not available	Methylthioadenosine phosphorylase.	0.878
ENSCAPP00000002499	SRM	ENSCAPP00000002499	ENSCAPP00000017599	annotation not available	Spermidine synthase.	0.918
ENSCAPP00000002499	UPP1	ENSCAPP00000002499	ENSCAPP00000009671	annotation not available	Uridine phosphorylase 1.	0.424
ENSCAPP00000002499	UPP2	ENSCAPP00000002499	ENSCAPP00000013452	annotation not available	Uridine phosphorylase 2.	0.424
ENSCAPP00000007765	ENSCAPP00000018695	ENSCAPP00000007765	ENSCAPP00000018695	annotation not available	annotation not available	0.855