Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGSF3Immunoglobulin superfamily member 3. (1213 aa)    
Predicted Functional Partners:
CDR2
Cerebellar degeneration related protein 2.
    
   0.841
GDAP2
Ganglioside induced differentiation associated protein 2.
    
 
 0.668
PDZRN3
PDZ domain containing ring finger 3.
    
 
 0.652
TTC12
Tetratricopeptide repeat domain 12.
    
 
 0.640
ANKK1
Ankyrin repeat and kinase domain containing 1.
    
 0.638
WDR3
WD repeat domain 3.
     
 0.617
CD9
CD9 molecule.
    
 0.572
UBXN11
UBX domain protein 11.
      
 0.570
TIAM2
TIAM Rac1 associated GEF 2.
    
 
 0.541
RNF112
Ring finger protein 112.
    
 0.535
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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