Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
THOP1Thimet oligopeptidase 1. (683 aa)    
Predicted Functional Partners:
KNG1
Kininogen 1.
     
 0.970
ACE
Angiotensin I converting enzyme.
     
 0.945
LUM
Lumican.
      
 0.939
CIB1
Calcium and integrin binding 1.
    
 
 0.898
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain.
      
 0.894
REN
Renin.
     
 0.880
HTR5A
5-hydroxytryptamine receptor 5A.
      
 0.858
ENSCAPP00000000088
annotation not available
     
 0.853
CTSE
Cathepsin E.
     
 0.853
ENSCAPP00000013720
annotation not available
     
 0.853
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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