Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TOPORSTOP1 binding arginine/serine rich protein. (987 aa)    
Predicted Functional Partners:
TP53
Tumor protein p53.
    
 
 0.962
TOP1
DNA topoisomerase I.
   
 
 0.935
PLK1
Polo like kinase 1.
    
 
 0.934
BLOC1S2
Biogenesis of lysosomal organelles complex 1 subunit 2.
     
 0.926
SUMO1
Small ubiquitin like modifier 1.
    
 0.925
SPIN1
Spindlin 1.
    
 
 0.920
MZT1
Mitotic spindle organizing protein 1.
    
  0.914
TUBGCP2
Tubulin gamma complex associated protein 2.
     
  0.913
TUBGCP4
Tubulin gamma complex associated protein 4.
     
  0.913
TUBGCP3
Tubulin gamma complex associated protein 3.
     
  0.913
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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