SETD2 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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Co-expression

Experiments

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[Homology]

Score

SETD2

SET domain containing 2, histone lysine methyltransferase. (2238 aa)

Predicted Functional Partners:

ENSCAPP00000014328

0.983

KMT2E

0.983

DOT1L

0.977

ENSCAPP00000003830

0.977

ENSCAPP00000012373

0.977

IWS1

0.967

SETD5

0.963

HTT

0.962

ENSCAPP00000001157

0.956

SUPT5H

0.954

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DOT1L	ENSCAPP00000003830	ENSCAPP00000002357	ENSCAPP00000003830	DOT1 like histone lysine methyltransferase.	annotation not available	0.975
DOT1L	ENSCAPP00000012373	ENSCAPP00000002357	ENSCAPP00000012373	DOT1 like histone lysine methyltransferase.	annotation not available	0.975
DOT1L	ENSCAPP00000014328	ENSCAPP00000002357	ENSCAPP00000014328	DOT1 like histone lysine methyltransferase.	annotation not available	0.932
DOT1L	KMT2E	ENSCAPP00000002357	ENSCAPP00000018689	DOT1 like histone lysine methyltransferase.	Lysine methyltransferase 2E.	0.874
DOT1L	SETD2	ENSCAPP00000002357	ENSCAPP00000006086	DOT1 like histone lysine methyltransferase.	SET domain containing 2, histone lysine methyltransferase.	0.977
DOT1L	SETD5	ENSCAPP00000002357	ENSCAPP00000011538	DOT1 like histone lysine methyltransferase.	SET domain containing 5.	0.871
ENSCAPP00000001157	ENSCAPP00000003830	ENSCAPP00000001157	ENSCAPP00000003830	annotation not available	annotation not available	0.840
ENSCAPP00000001157	ENSCAPP00000012373	ENSCAPP00000001157	ENSCAPP00000012373	annotation not available	annotation not available	0.840
ENSCAPP00000001157	IWS1	ENSCAPP00000001157	ENSCAPP00000009906	annotation not available	Interacts with SUPT6H, CTD assembly factor 1.	0.981
ENSCAPP00000001157	SETD2	ENSCAPP00000001157	ENSCAPP00000006086	annotation not available	SET domain containing 2, histone lysine methyltransferase.	0.956
ENSCAPP00000001157	SUPT5H	ENSCAPP00000001157	ENSCAPP00000006127	annotation not available	SPT5 homolog, DSIF elongation factor subunit.	0.995
ENSCAPP00000003830	DOT1L	ENSCAPP00000003830	ENSCAPP00000002357	annotation not available	DOT1 like histone lysine methyltransferase.	0.975
ENSCAPP00000003830	ENSCAPP00000001157	ENSCAPP00000003830	ENSCAPP00000001157	annotation not available	annotation not available	0.840
ENSCAPP00000003830	ENSCAPP00000012373	ENSCAPP00000003830	ENSCAPP00000012373	annotation not available	annotation not available	0.870
ENSCAPP00000003830	ENSCAPP00000014328	ENSCAPP00000003830	ENSCAPP00000014328	annotation not available	annotation not available	0.816
ENSCAPP00000003830	KMT2E	ENSCAPP00000003830	ENSCAPP00000018689	annotation not available	Lysine methyltransferase 2E.	0.858
ENSCAPP00000003830	SETD2	ENSCAPP00000003830	ENSCAPP00000006086	annotation not available	SET domain containing 2, histone lysine methyltransferase.	0.977
ENSCAPP00000003830	SETD5	ENSCAPP00000003830	ENSCAPP00000011538	annotation not available	SET domain containing 5.	0.807
ENSCAPP00000003830	SUPT5H	ENSCAPP00000003830	ENSCAPP00000006127	annotation not available	SPT5 homolog, DSIF elongation factor subunit.	0.565
ENSCAPP00000012373	DOT1L	ENSCAPP00000012373	ENSCAPP00000002357	annotation not available	DOT1 like histone lysine methyltransferase.	0.975