STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPG21SPG21 abhydrolase domain containing, maspardin. (286 aa)    
Predicted Functional Partners:
TECPR2
Tectonin beta-propeller repeat containing 2.
      
 0.586
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.572
SPG11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.570
ALDH16A1
Aldehyde dehydrogenase 16 family member A1.
      
 0.562
NIPA1
NIPA magnesium transporter 1.
      
 0.555
ENSCAPP00000005210
annotation not available
      
 0.553
AP5Z1
Adaptor related protein complex 5 subunit zeta 1.
      
 0.522
AKIRIN2
Akirin 2.
    
   0.482
RAB7A
RAB7A, member RAS oncogene family.
    
   0.465
GPC3
Glypican 3.
      
 0.426
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.