Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPG21SPG21 abhydrolase domain containing, maspardin. (286 aa)    
Predicted Functional Partners:
RAB7A
RAB7A, member RAS oncogene family.
    
   0.887
ALDH16A1
Aldehyde dehydrogenase 16 family member A1.
      
 0.818
AKIRIN2
Akirin 2.
    
   0.815
ENSCAPP00000018474
annotation not available
    
   0.773
SPG11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.751
ENSCAPP00000005210
annotation not available
      
 0.729
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.689
B3GALT2
Beta-1,3-galactosyltransferase 2.
      
 0.686
GPC3
Glypican 3.
      
 0.665
SLC2A9
Solute carrier family 2 member 9.
      
 0.662
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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