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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDGFAPlatelet derived growth factor subunit A. (189 aa)    
Predicted Functional Partners:
PDGFRA
Platelet derived growth factor receptor alpha.
    
 0.982
PDGFRB
Platelet derived growth factor receptor beta.
    
 0.973
PDGFB
Platelet derived growth factor subunit B.
    
0.969
PDGFC
Platelet derived growth factor C.
     
 0.957
PDGFD
Platelet derived growth factor D.
     
 0.956
FLT3
Fms related tyrosine kinase 3.
    
 0.932
VEGFC
Vascular endothelial growth factor C.
     
 0.929
KIT
KIT proto-oncogene, receptor tyrosine kinase.
    
 0.920
VEGFB
Vascular endothelial growth factor B.
     
 0.915
INSR
Insulin receptor.
    
  0.915
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.