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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIR1Corepressor interacting with RBPJ, 1. (379 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.906
ENSCAPP00000012207
annotation not available
   
 
 0.905
SAP30
Sin3A associated protein 30.
    
 0.897
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.882
SAP30L
SAP30 like.
    
 0.879
CWC25
CWC25 spliceosome associated protein homolog.
   
 
 0.878
NCOR2
Nuclear receptor corepressor 2.
    
 0.863
HDAC2
Histone deacetylase 2.
    
 0.842
HDAC1
Histone deacetylase 1.
    
 0.841
DHX38
DEAH-box helicase 38.
   
 
 0.824
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.