CASP6 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Gene Fusion

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Experiments

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[Homology]

Score

CASP6

Caspase 6. (285 aa)

Predicted Functional Partners:

CASP10

0.983

CASP8

0.983

CASP9

0.981

ENSCAPP00000008032

0.970

LMNA

0.970

APAF1

0.942

APP

0.905

ENSCAPP00000012429

0.902

ENSCAPP00000001423

0.901

LMNB1

0.901

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	CASP10	ENSCAPP00000013715	ENSCAPP00000003418	Apoptotic peptidase activating factor 1.	Caspase 10.	0.942
APAF1	CASP6	ENSCAPP00000013715	ENSCAPP00000006130	Apoptotic peptidase activating factor 1.	Caspase 6.	0.942
APAF1	CASP8	ENSCAPP00000013715	ENSCAPP00000009261	Apoptotic peptidase activating factor 1.	Caspase 8.	0.942
APAF1	CASP9	ENSCAPP00000013715	ENSCAPP00000000581	Apoptotic peptidase activating factor 1.	Caspase 9.	0.999
APAF1	ENSCAPP00000008032	ENSCAPP00000013715	ENSCAPP00000008032	Apoptotic peptidase activating factor 1.	annotation not available	0.999
APP	CASP6	ENSCAPP00000002952	ENSCAPP00000006130	Amyloid beta precursor protein.	Caspase 6.	0.905
APP	CASP9	ENSCAPP00000002952	ENSCAPP00000000581	Amyloid beta precursor protein.	Caspase 9.	0.407
APP	ENSCAPP00000008032	ENSCAPP00000002952	ENSCAPP00000008032	Amyloid beta precursor protein.	annotation not available	0.930
APP	ENSCAPP00000012429	ENSCAPP00000002952	ENSCAPP00000012429	Amyloid beta precursor protein.	annotation not available	0.992
CASP10	APAF1	ENSCAPP00000003418	ENSCAPP00000013715	Caspase 10.	Apoptotic peptidase activating factor 1.	0.942
CASP10	CASP6	ENSCAPP00000003418	ENSCAPP00000006130	Caspase 10.	Caspase 6.	0.983
CASP10	CASP9	ENSCAPP00000003418	ENSCAPP00000000581	Caspase 10.	Caspase 9.	0.946
CASP10	ENSCAPP00000001423	ENSCAPP00000003418	ENSCAPP00000001423	Caspase 10.	annotation not available	0.407
CASP10	ENSCAPP00000008032	ENSCAPP00000003418	ENSCAPP00000008032	Caspase 10.	annotation not available	0.989
CASP10	ENSCAPP00000012429	ENSCAPP00000003418	ENSCAPP00000012429	Caspase 10.	annotation not available	0.406
CASP10	LMNA	ENSCAPP00000003418	ENSCAPP00000014374	Caspase 10.	Lamin A/C.	0.433
CASP10	LMNB1	ENSCAPP00000003418	ENSCAPP00000008136	Caspase 10.	Lamin B1.	0.407
CASP6	APAF1	ENSCAPP00000006130	ENSCAPP00000013715	Caspase 6.	Apoptotic peptidase activating factor 1.	0.942
CASP6	APP	ENSCAPP00000006130	ENSCAPP00000002952	Caspase 6.	Amyloid beta precursor protein.	0.905
CASP6	CASP10	ENSCAPP00000006130	ENSCAPP00000003418	Caspase 6.	Caspase 10.	0.983