Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
STYK1Serine/threonine/tyrosine kinase 1. (293 aa)    
Predicted Functional Partners:
ERBB2
Erb-b2 receptor tyrosine kinase 2.
    
  0.868
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component.
      
 0.747
ENSCAPP00000002769
annotation not available
    
 0.717
MET
MET proto-oncogene, receptor tyrosine kinase.
    
  0.607
MST1R
Macrophage stimulating 1 receptor.
    
  0.607
KITLG
KIT ligand.
    
 0.591
SGK3
Serum/glucocorticoid regulated kinase family member 3.
    
 
 0.572
SSBP2
Single stranded DNA binding protein 2.
      
 0.569
CSF1
Colony stimulating factor 1.
    
 0.554
UBE4B
Ubiquitination factor E4B.
    
 
 0.554
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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