Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAPK6Mitogen-activated protein kinase 6. (716 aa)    
Predicted Functional Partners:
ENSCAPP00000013355
annotation not available
    
 0.996
MAPK4
Mitogen-activated protein kinase 4.
   
 
  0.994
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
    
 
 0.963
ENSCAPP00000007687
annotation not available
    
 
 0.962
PAK2
P21 (RAC1) activated kinase 2.
   
 0.947
MAPK3
Mitogen-activated protein kinase 3.
    
  0.945
CDK1
Cyclin dependent kinase 1.
   
 0.939
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.937
ENSCAPP00000003757
annotation not available
    
 0.936
ENSCAPP00000003915
annotation not available
    
 0.935
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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