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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HRH3Histamine receptor H3. (403 aa)    
Predicted Functional Partners:
HRH2
Histamine receptor H2.
    
0.852
HRH1
Histamine receptor H1.
     
0.687
CHRM4
Cholinergic receptor muscarinic 4.
     
0.670
HRH4
Histamine receptor H4.
     
0.657
CHRM2
Cholinergic receptor muscarinic 2.
  
  
0.558
DRD2
Dopamine receptor D2.
   
0.556
HDC
Histidine decarboxylase.
   
  
 0.553
HNMT
Histamine N-methyltransferase.
      
 0.518
DRD1
Dopamine receptor D1.
    
0.492
ADORA2A
Adenosine A2a receptor.
    
  0.469
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.