close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC3Arrestin domain containing 3. (338 aa)    
Predicted Functional Partners:
ENSCAPP00000011344
annotation not available
    
 
 0.953
ENSCAPP00000006417
annotation not available
    
 0.721
ENSCAPP00000009620
annotation not available
    
 0.718
ENSCAPP00000010372
annotation not available
    
 0.718
ENSCAPP00000013812
annotation not available
    
 0.718
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.705
NLRP3
NLR family pyrin domain containing 3.
    
 0.681
WWP2
WW domain containing E3 ubiquitin protein ligase 2.
    
 
 0.677
DNAJC10
DnaJ heat shock protein family (Hsp40) member C10.
    
 0.580
ITGAL
Integrin subunit alpha L.
      
 0.563
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.