Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC3Arrestin domain containing 3. (338 aa)    
Predicted Functional Partners:
WWP2
WW domain containing E3 ubiquitin protein ligase 2.
    
 
 0.969
ENSCAPP00000011344
annotation not available
    
 
 0.966
WWP1
WW domain containing E3 ubiquitin protein ligase 1.
    
 
 0.961
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.961
ITCH
Itchy E3 ubiquitin protein ligase.
    
 
 0.961
CUEDC1
CUE domain containing 1.
    
   0.921
ITGAL
Integrin subunit alpha L.
      
 0.849
ARRB2
Arrestin beta 2.
    
 
 0.836
TOM1
Target of myb1 membrane trafficking protein.
    
 
 0.831
F2R
Coagulation factor II thrombin receptor.
    
 
 0.807
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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