Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AP1S1Adaptor related protein complex 1 subunit sigma 1. (157 aa)    
Predicted Functional Partners:
AP1B1
Adaptor related protein complex 1 subunit beta 1.
    
 0.999
AP1G1
Adaptor related protein complex 1 subunit gamma 1.
    
 0.998
AP1G2
Adaptor related protein complex 1 subunit gamma 2.
    
 0.998
AP2B1
Adaptor related protein complex 2 subunit beta 1.
    
 0.996
ENSCAPP00000007639
annotation not available
   
  0.995
CLTA
Clathrin light chain A.
   
 0.992
CLTB
Clathrin light chain B.
   
 0.992
AP1M2
Adaptor related protein complex 1 subunit mu 2.
    
 0.991
AP1M1
Adaptor related protein complex 1 subunit mu 1.
    
 0.991
ENSCAPP00000000946
annotation not available
    
 0.989
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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