STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIAS1Protein inhibitor of activated STAT 1. (615 aa)    
Predicted Functional Partners:
SUMO1
Small ubiquitin like modifier 1.
    
 0.998
STAT1
Signal transducer and activator of transcription 1.
    
 0.998
STAT3
Signal transducer and activator of transcription 3.
    
 0.989
TP53
Tumor protein p53.
    
 0.987
ENSCAPP00000013457
annotation not available
    
 0.980
PIAS4
Protein inhibitor of activated STAT 4.
    
  0.975
ENSCAPP00000013163
annotation not available
    
 0.973
STAT4
Signal transducer and activator of transcription 4.
    
 0.973
ENSCAPP00000004258
annotation not available
   
  0.963
ENSCAPP00000007617
annotation not available
   
  0.963
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.