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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MIER1MIER1 transcriptional regulator. (502 aa)    
Predicted Functional Partners:
CDYL
Chromodomain Y like.
   
 
 0.850
HDAC1
Histone deacetylase 1.
    
 
 0.842
HDAC2
Histone deacetylase 2.
    
 
 0.771
BAHD1
Bromo adjacent homology domain containing 1.
    
 
 0.712
CDYL2
Chromodomain Y like 2.
   
 
 0.638
DNTTIP1
Deoxynucleotidyltransferase terminal interacting protein 1.
    
 
 0.606
SIN3B
SIN3 transcription regulator family member B.
    
 
 0.592
ANGEL2
Angel homolog 2.
   
  
 0.583
ANAPC15
Anaphase promoting complex subunit 15.
      
 0.565
ENSCAPP00000006365
annotation not available
    
   0.557
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.