Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MIER1MIER1 transcriptional regulator. (502 aa)    
Predicted Functional Partners:
CDYL
Chromodomain Y like.
    
 
 0.979
BAHD1
Bromo adjacent homology domain containing 1.
    
 
 0.978
HDAC1
Histone deacetylase 1.
    
 0.976
HDAC2
Histone deacetylase 2.
    
 0.974
EHMT2
Euchromatic histone lysine methyltransferase 2.
    
   0.959
ARID5B
AT-rich interaction domain 5B.
    
   0.959
ENSCAPP00000006365
annotation not available
    
   0.958
MIER3
MIER family member 3.
    
   0.936
H2AZ2
H2A.Z variant histone 2.
   
   0.854
EHMT1
Euchromatic histone lysine methyltransferase 1.
    
   0.841
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]