Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UBE2ZUbiquitin conjugating enzyme E2 Z. (339 aa)    
Predicted Functional Partners:
UBA6
Ubiquitin like modifier activating enzyme 6.
  
 0.995
UBA1
Ubiquitin like modifier activating enzyme 1.
  
 0.979
UBA7
Ubiquitin like modifier activating enzyme 7.
  
 0.919
WDR12
WD repeat domain 12.
    
 0.896
ENSCAPP00000004359
annotation not available
    
   0.868
ENSCAPP00000015096
annotation not available
    
  0.851
SQSTM1
Sequestosome 1.
   
  0.846
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 
 0.837
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.837
ENSCAPP00000007672
annotation not available
     
 0.831
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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