Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
KCNK2Potassium two pore domain channel subfamily K member 2. (415 aa)    
Predicted Functional Partners:
POPDC3
Popeye domain containing 3.
     
 0.948
POPDC2
Popeye domain containing 2.
     
 0.948
BVES
Blood vessel epicardial substance.
     
 0.935
KCNK10
Potassium two pore domain channel subfamily K member 10.
     
 0.911
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
     
 0.878
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
     
 0.878
KCNK4
Potassium two pore domain channel subfamily K member 4.
     
 0.665
KCNK1
Potassium two pore domain channel subfamily K member 1.
     
 0.657
KCNK18
Potassium two pore domain channel subfamily K member 18.
     
 0.626
FAM110A
Family with sequence similarity 110 member A.
      
 0.615
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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