Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL1RL2Interleukin 1 receptor like 2. (483 aa)    
Predicted Functional Partners:
IL1RAP
Interleukin 1 receptor accessory protein.
   
 0.992
MYD88
MYD88 innate immune signal transduction adaptor.
    
 0.989
IRAK1
Interleukin 1 receptor associated kinase 1.
    
 0.989
TRAF6
TNF receptor associated factor 6.
   
 0.985
ENSCAPP00000012152
annotation not available
    
 0.984
IL36RN
Interleukin 36 receptor antagonist.
    
 0.977
ENSCAPP00000004229
annotation not available
    
 0.969
DSG1
Desmoglein 1.
      
 0.932
ENSCAPP00000007829
annotation not available
    
 0.888
IL1R2
Interleukin 1 receptor type 2.
   
 
 0.873
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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